Summary

1. Calaos - designed as a full-stack home automation platform, including a server application, touchscreen interface, web application, native mobile applications for iOS and Android
2. Domoticz - a home automation system with a pretty wide library of supported devices, ranging from weather stations to smoke detectors to remote controls, and a large number of additional third-party integrations are documented on the project's website
3. Home Assistant - open source home automation platform designed to be easily deployed on almost any machine that can run Python 3, from a Raspberry Pi to a network-attached storage (NAS) device
4. MisterHouse - uses Perl scripts to monitor anything that can be queried by a computer or control anything capable of being remote controlled
5. OpenHAB - short for Open Home Automation Bus, is one of the best-known home automation tools among open source enthusiasts, with a large user community and quite a number of supported devices and integrations; written in Java
6. OpenMotics - home automation system designed to provide a comprehensive system for controlling devices, rather than stitching together many devices from different providers.